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This teaching unit represents a completely new set of over 240 images that illustrate the causes, diagnosis and management of autoimmune injury to the liver and biliary tree. The outstanding photographs, micrographs, and illustrations explain important concepts in our understanding of the underlying pathophysiology of primary biliary cirrhosis, primary sclerosing cholangitis, and autoimmune hepatitis. Evidence-based management algorithms for these disorders will aid the clinician in caring for patients. Moreover, the underlying pathophysiology is used to provide a scientific basis for rational treatment strategies. Images, including graphic representations of data from key studies, are accompanied by explanatory legends that contain recent literature citations, thereby providing a unique teaching and self-educational resource. Clinical cases provide a framework for using the slides to teach practicing clinicians, fellows, residents and medical students. The senior author, Keith Lindor, MD, is Professor of Medicine, Mayo Clinic College of Medicine, Rochester, MN.
GTP Autoimmune Liver Disease is separated into the following sections: Part I: Primary Sclerosing Cholangitis; Part II: Primary Biliary Cirrhosis; Part III: Autoimmune Hepatitis; Part IV: Overlap Syndromes; Part V: Illustrative Cases.
Senior Author:
Keith Lindor, MD
Professor of Medicine
Mayo Clinic College of Medicine
Rochester, MN
Co-Authors:
Jayant A. Talwakar, MD
Associate Professor of Medicine
Mayo Clinic College of Medicine
Rochester, MN
Jenny Heathcote, MD, FRCP, FRCP(C)
Professor of Medicine
University of Toronto
Toronto, ON Canada
Dwain Thiele, MD
Professor of Internal Medicine
University of Texas Southwestern Medical Center
Dallas, TX
Elizabeth M. Brunt, MD
Professor of Pathology
Saint Louis University School of Medicine
St. Louis, MO
Artist:
Jerry Schoendorf, MAMS
Chapel Hill, NC
Acknowledgements:
The authors thank Dr. Jean-Pierre Raufman for providing the clinical cases and for his helpful comments.
April 1, 2006