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This teaching unit represents a completely new set of over 400 images that illustrate the consequences of advanced liver disease, with a focus on the causes, diagnosis and management of cirrhosis and its most common complication, portal hypertension. The outstanding photographs, micrographs, illustrations and movies explain important concepts in our understanding of the underlying pathophysiology of cirrhosis and portal hypertension. Management algorithms for common complications will aid the clinician in patient management. Moreover, the underlying pathophysiology is used to provide a scientific basis for treatment strategies. Images, including graphic representations of data from key studies, are accompanied by explanatory legends that contain recent literature citations, thereby providing a unique teaching and self-educational resource. The senior author, Guadelupe Garcia-Tsao, MD, is Professor of Medicine, Yale University School of Medicine and the VA Connecticut Healthcare System, New Haven, CT.
GTP Cirrhosis and Portal Hypertension is separated into the following sections: Part I: Cirrhosis: Definition, Natural History and Diagnosis; Part II: Pathophysiology and Types of Portal Hypertension; Part III: Hyperdynamic Circulatory State; Part IV: Varices and variceal hemorrhage; Part V: Ascites; Part VI: Spontaneous Bacterial Peritonitis; Part VII: Hepatorenal Syndrome; Part VIII: Hepatic Encephalopathy; Part IX: Hepatopulmonary Syndrome; Part X: Portopulmonary Hypertension; Part XI: Liver Transplant.
Senior Author:
Guadalupe Garcia-Tsao, M.D.
Professor of Medicine
Yale University School of Medicine
VA Connecticut Healthcare System
New Haven CT
Co-Authors:
Suchat Wongcharatrawee, M.D.
Assistant Professor of Medicine
Yale University School of Medicine
VA Connecticut Healthcare System
New Haven CT
Patrick S. Kamath, M.D.
Professor of Medicine
Mayo Clinic College of Medicine
Rochester MN
Artists:
Jerry Schoendorf, MAMS
Chapel Hill, NC
Stan Coffman
Durham, NC
Acknowledgements:
The authors thank Dr. Michel Wong Kee Song for endoscopic pictures and Dr. Dhanpat Jain for having provided histological images. The authors also thank the following for reviewing the content of this unit and for many helpful suggestions: Drs. Jean-Pierre Raufman, Roberto Groszmann and Fred Gorelick. We thank Dr. James B. McGee for providing the template for clinical cases and for his helpful comments.
September 9, 2005