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This teaching unit represents a completely new set of images that illustrate the epidemiology, physiology, diagnosis and treatment of a rapidly emerging health concern: non-alcoholic fatty liver disease (NAFLD), including non-alcoholic steatohepatitis (NASH). The outstanding photographs, micrographs, illustrations and animations explain important concepts in our understanding of the metabolic factors that lead to fat deposition and liver dysfunction. These images provide a scientific basis for the treatment of NAFLD and the prevention of complications, including cirrhosis, portal hypertension and liver cancer. Images, including graphic representations of data from key studies, are accompanied by explanatory legends that contain recent literature citations, thereby providing a unique teaching and self-educational resource. The senior author, Anna Mae Diehl, MD, is Professor of Medicine and Chief of the Division of Gastroenterology, Duke University School of Medicine, Durham, NC.
GTP Non-Alcoholic Fatty Liver Disease is separated into the following sections: Part I: Introduction, Epidemiology and Definitions; Part II: Pathophysiology: Part III: Diagnosis and Treatment; Part IV: Illustrative Cases.
Anna Mae Diehl, M.D. is Professor of Medicine at Duke University School of Medicine, Durham, NC. Dr. Diehl did her GI and Hepatology clinical Fellowship at Johns Hopkins School of Medicine. She joined the faculty at Johns Hopkins in 1990 and moved to Duke University in 2004. Dr. Diehl is widely recognized in the field of hepatology and has a particular research interest in non-alcoholic fatty liver disease. She has served on the national advisory council for the National Institute on Alcohol Abuse and Alcoholism; national and international grant review panels; and scientific advisory boards for NIH. She is a recipient of the Leon Schiff Prize for outstanding research in clinical liver disease from the American Association for the Study of Liver Diseases and the Hans Popper Prize for outstanding basic liver research from the International Association for the Study of Liver Diseases. Dr. Diehl`s research is supported by the National Institutes of Health.
Jerry Schoendorf, MAMS
Chapel Hill, NC
The author thanks Dr. James B. McGee, University of Pittsburgh School of Medicine, for providing the template for clinical cases and for his helpful comments, and Dr. Jean-Pierre Raufman, University of Maryland School of Medicine, for providing some of the micrographs and for reviewing and editing the unit.
May 15, 2005